渡辺　知保　Chiho Watanabe

職　歴

1989年 8月　　東北大学医学部衛生学講座助手
1997年12月　　東京大学大学院医学系研究科人類生態学助教授
（1998年6～9月　米国ニューヨーク州ロチェスター大学客員研究員）
2005年４月　　東京大学大学院医学系研究科人類生態学教授（現在に至る）

学　歴

1982年 3月 東京大学医学部保健学科卒業
1984年 3月 同大学大学院　医学系研究科修士課程修了
1987年～88年　米国ニューヨーク州ロチェスター大大学院留学
1989年 8月 東京大学大学院医学系研究科博士課程単位取得済退学
1991年 1月 保健学博士号取得（東京大学）

主な研究領域

＊化学物質への周産期曝露の発達神経毒性：
主として低濃度の重金属（メチル水銀，カドミウム，砒素）を対象としている
＊化学物質毒性の修飾因子：
特に必須微量元素（セレン）あるいは低栄養などの栄養学的要因，遺伝的要因，性・加齢など生理的要因
＊砒素汚染と健康影響：バングラデシュ・ネパール
＊小児環境保健：インドネシア
＊生業活動と化学物質汚染との相互関連性：インドネシアなど

ひとこと

人類生態学という言葉が使われたのはそれほど最近のことではないが，例えば生理学や公衆衛生学のように， 領域名を述べただけで誰にでも（正しいかどうかはさておき）理解してもらえるような学問でないのも事実です． 地球が相対的に狭くなり，人類の住処のboundary が学問的にも社会的にも十分に認識されるようになってくると， ひとつの地域・ひとつの問題をとりあげているつもりで，その背後に実にさまざまなほかの地域・ほかの問題が ぞろぞろとついてくるようなこと，あるいはひとつの地域と思った空間・集団の中でも問題の程度や性質が 均一でないようなことが増えてくるように思われます.そういった，要因と要因が影響しあい，ストレートな因果関係で 記述しにくい問題，あるいは集団の平均値よりも集団の中の偏差とその原因を重視するような問題は， 人類生態学がこれまで手がけてきた地域生態系の構造解明という課題にも共通しており， そうした意味でこれから人類生態学がチャレンジすべき課題はそこら中にころがっているように感じます． こういう問題群に解答を出すことによって，人類生態学をやっているということが，生理学や公衆衛生学をやっている， というのと同程度とはいかなくとも，すんなり理解されるようにしたい，と思っています．最後に， こういった学問領域に興味をよせてくれる若い人には，関心は広く，しかしspecificであることが重要だということを 強調しておきたいと思います．

＜連絡先＞　E-mail:chiho<at>humeco.m.u-tokyo.ac.jp

業績（発表論文）

( 更新日 2012年7月6日 )

原著論文（英文） | 原著論文（和文） | 総説（英文） | 総説（和文） | 単行本分担執筆（英文・和文）

  • ■　原著論文（英文）
  • Vengiau G, Umezaki M, Phuanukoonnon S, Siba P. and Watanabe C. (in press). Diet and physical activity among migrant Bougainvilleans in Port Moresby, Papua New Guinea: association with anthropometric measures and blood pressure. American Journal of Human Biology.
  • Parajuli RP, Umezaki M, and Watanabe C. Diet among people in the Terai region of Nepal, an area of micronutrient deficiency. Journal fo Biosocial Science. 44(4):401-415
  • Minoru YOSHIDA, Masako HONDA, Chiho WATANABE, Masahiko SATOH, Akira YASUTAKE: Neurobehavioral changes and alteration of gene expression in the brains of metallothionein-I/II mice exposed to low levels of mercury vapor during posnatal development. Journal of Toxicological Sciences. 36(5) 539-547 (2011)
  • Konishi S, Parajuli RP, Takane E, Maharjan M, Sharma S, Tachibana K, Jiang HW, Pahari K, Pandey BD, and Watanabe C. Health status of married women residing five communities in Nepal: Unexpectedly high prevalence of anemia in a well-off community of Kathmandu. Nepal Medical College Journal.13(1):1-6.
  • Konishi S, Watanabe C, Umezaki M and Ohtsuka R (2011) Energy and nutrient intake of Tongan adults estimated by 24-hour recall: The importance of local food. Ecology of Food and Nutrition 50:337-350.
  • Yoshida M, Suzuki M, Satoh M, Yasutake A, and Watanabe C. (2011) Neurobehavioral effects of combined prenatal exposure to low-level mercury vapor and methylmercury. The Journal of Toxicological Science.Vol. 36, No. 1 January 73-80 link
  • Yoshinaga, J., Takagi, M., Yamasaki, K., Tamiya, S., Watanabe, C., and Kaji, M. Blood lead levels of contemporary Japanese children. Environmental Health and Preventive Medicine.17(1):27-33
  • Inoue, Y., Umezaki, M.,and Watanabe, C. Emergence of income inequality and its impact on subjective quality of life in an ethnic minority community in Hainan Island, China. Anthropological Science.120(2012)51-60
  • Ohtani-Kaneko R, Iwakura T, Iwafuchi M, Muraoka D,Yokosuka M, Shiga T, Watanabe C. (2010) In vitro effects of bisphenol A on developing hypothalamic neurons.Toxicology.272(1-3):52-58
  • Parajuli RP, Umezaki M, and Watanabe C (2009) Behavioral and Nutritional Factors and Geohelminth Infection among Two Ethnic Groups in the Terai Region, Nepal. American Journal of Human Biology 21, 98-104
  • Suzuki Y, Niwa M, Yoshinaga J, Watanabe C, Mizumoto Y, Serizawa S, Shiraishi H. (2009) Exposure assessment of phtalate esters in Japanses pregnant women by using urinary metabolite analysis. Environmental Health and Preventive Medicine 14, 180-187
  • Ohtani-Kaneko R, Iwafuchi M, Iwakura T, Muraoka D, Yokosuka M, Shiga T, Watanabe C. (2009) Effects of estrogen on synapsin I distribution in developing hypothalamic neurons.Neurosci Res. 66(2):180-188
  • Yoshioka W, Akagi T, Nishimura N, Shimizu H, Watanabe C, and Tohyama C.(2009) Severe toxicity and cycolooxiygenase (COX)-2 mRNA increase by lithium in the neonatal mouse kidney. Journal of Toxicological Sciences 34, 519-525
  • Fukuyama, S., Watanabe, C., Umezaki, M., Ohtsuka, R. (2009) Twenty years' demographic change in sedentes and migrants of an international migrant-sending community in Tonga. Journal of Biosocial Science, 41(1):71-81
  • Parajuli, RP., Umezaki, M. and Watanabe, C. (2008) Behavioral and Nutritional Factors and Geohelminth Infection among Two Ethnic Groups in the Terai Region, Nepal. American Journal of Human Biology, 21: 98-104.
  • Yokosuka, M., Ohtani-Kaneko, R., Yamashita, K., Muraoka, D., Kuroda, Y., and Watanabe, C. (2008) Estrogen and environmental estrogenic chemicals exert developmental effects on rat hypothalamic neurons and glias. Toxicology In Vitro, 22: 1-9.
  • Hirano, M., Kitamura, K., Kato, I., Yanaihara, C., Iwamoto, K., Sekiyama, M., Watanabe C., Nakamoto, T., Miyamoto, N., Onishi, Y. and Arizono, K. (2008) Development of enzyme immunoassay for detection of DDT. Journal of Environmental Science and Health Part A, 43: 44-9.
  • Ohtani-Kaneko, R., Tazawa, H., Yokosuka, M., Yoshida, M., Satoh, M. and Watanabe, C. (2008) Suppressive effects of cadmium on neurons, affected proteins in cultured developing cortical cells. Toxicology, 253: 110-116.
  • Yoshida, M., Shimizu, N., Suzuki, M., Watanabe, C., Satoh, M., Mori, K. and Yasutake, A. (2008) Emergence of methylmercury toxicity long after perinatal exposure in meallothionein-null and wild-type C57BL mice strains. Environmental Health Perspectives, 116: 746-751.
  • Mean-Heang, N.G.Y., Nakamura, K., Ohnishi, M., Kizuki, M., Suyama, S., Seino, K., Inose, T., Umezaki, M., Watanabe, M. and Takano, T. (2007) Improved perinatal health through qualified antenatal care in urban Phnom Penh, Cambodia. Environmental Health and Preventive Medicine, 12: 193-201.
  • Umezaki, M., Sengebau-Kinzio, M.J., Nakamura, K., Ridep, E., Watanabe, M. and Takano, T. (2007) Household risk factors associated with dengue-like illness. Republic of Palau, 2000-2001. BioScience Trends, 1: 33-37.
  • Ishitobi, H., Mori, K., Yoshida, K. and Watanabe, C. (2007) Effects of perinatal exposure to low-dose cadmium on thyroid hormone-related and sex hormone receptor gene expressions in brain of offspring. Neurotoxicology, 28: 790-797.
  • Mori, K., Yoshida, K., Nakagawa, Y., Hoshikawa, S., Ozaki, H., Ito, S. and Watanabe, C (2007) Methylmercury inhibition of type II5’-deiodinase activity resulting in a decrease in growth hormone production in GH3 cells. Toxicology, 237: 203-209.
  • Maharjan, M., Watanabe, C., Ahmad, S.A. Umezaki, M. and Ohtsuka, R. (2007) Mutual interaction between nutritional status and chronic arsenic toxicity due to groundwater contamination in an area of Terai, lowland Nepal. Journal of Epidemiology and Community Health, 61: 389-394.
  • Watanabe, C., Matsui, T., Inaoka, T., Kadono, T., Miyazaki, K., Bae, MJ., Ono, T., Ohtsuka, R., and A.T.M., Bokul. (2007) Dermatological and Nutritional/growth Effects among Children Living in Arsenic-contaminated Communities in Rural Bangladesh. Journal of Environmental Science and Health, Part A Vol. A42: 1835-41.
  • Sekiyama, M., Tanaka, M., Gunawan, B., Abdoellah, O. and Watanabe, C. (2007) Pesticide Usage and Its Association with Health Symptoms among Farmers in Rural Villages in West Java, Indonesia. Environmental Sciences, 14:23-34.
  • Maharjan, M., Roshan, R., Shrestha1, Ahmad, S.K.A., Watanabe, C. and Ohtsuka, R. (2007) Prevalence of Arsenicosis in Terai, Nepal. Journal of Health Population and Nutrition, 24(2).
  • Dewanti L, Watanabe C, Sulistiawati, Ohtsuka R. (2006) Unexpected changes in blood pressure and hematological parameters among fasting and nonfasting workers during Ramadan in Indonesia. European Journal of Clinical Nutrition.
  • Mori, K., Yoshida, K., Hoshikawa, S., Ito, S., Yoshida, M., Satoh, M., Watanabe, C. (2006) Effects of perinatal exposure to low doses of cadmium or methylmercury on thyroid hormone metabolism in metallothionein-deficient mouse neonates. Toxicology, 228: 77-84.
  • Mori, K., Yoshida, K., Tani, J.I., Hoshikawa, S., Ito, S., Watanabe, C. (2006) Methylmercury inhibits type II 5'-deiodinase activity in NB41A3 neuroblastoma cells. Toxicology Letters, 161: 96-101.
  • Takeuchi, S., Li, Y., He, Y., Zhou, H., Moji, K., Ohtsuka, R. and Watanabe, C. (2006) Behaviors associated with water contact and Schistosoma japonicum infection in a rural village, the Dongting Lake region, China. Tropical Medicine and Health, 34(3):117-123.
  • Yoshida M, Watanabe C, Kishimoto M, Yasutake A, Satoh M, Sawada M, Akama Y (2006) Behavioral changes in metallothionein-null mice after the cessation of long-term, low-level exposure to mercury vapor. TOXICOLOGY LETTERS 161 (3): 210-218.
  • Tanaka, M., Umezaki, M., Natsuhara, K., Yamauchi, T., Inaoka, T., Hongo, T., Nagano, M., Watanabe, C., and Ohtsuka, R. (2005) No difference in serum leptin concentrations between urban-dwelling Austronesians and Non-Austronesians in Papua New Guinea. American Journal of Human Biology, 17: 696-703.
  • Maharjan, M., Watanabe, C., Ahmad, A., Ohtsuka, R. (2005) Arsenic contamination in drinking water and skin manifestations in lowland Nepal: the first community-based survey. American Journal of Tropical Medicine and Hygiene, 73: 477-479.Ishitobi, H. and Watanabe C. (2005) Effects of low-dose perinatal cadmium exposure on tissue zinc and copper concentrations in neonatal mice and on the reproductive development of female offspring. Toxicology Letters, 159: 38-46.
  • Ishitobi, H. and Watanabe C. (2005) Effects of low-dose perinatal cadmium exposure on tissue zinc and copper concentrations in neonatal mice and on the reproductive development of female offspring. Toxicology Letters, 159: 38-46.
  • Miyazaki, K., Watanabe, C., Mori, K., Yoshida, K. and Ohtsuka, R. (2005) The effects of gestational arsenic exposure and dietary selenium deficiency on selenium and selenoenzymes in maternal and fetal tissues in mice. Toxicology. 208(3):357-365.
  • Sudo, N., Sekiyama, M., Watanabe, C., Bokul, AT. and Ohtsuka, R. (2004) Gender differences in food and energy intake among adult villagers in northwestern Bangladesh: a food frequency questionnaire survey. International Journal of Food Sciences & Nutrition. 55(6):499-509.
  • hmad, SA., Maharjan, M., Watanabe, C. and Ohtsuka, R. (2004) Arsenicosis in two villages in Terai, lowland Nepal. Environmental Sciences. 11(3):179-188.
  • Watanabe, C., Kawata, A., Sudo, N., Sekiyama, M., Inaoka, T., Bae, M. and Ohtsuka, R. (2004) Water intake in an Asian population living in arsenic-contaminated area. Toxicology & Applied Pharmacology. 198(3):272-282.
  • Ohtsuka, R., Sudo, N., Sekiyama, M., Watanabe, C., Inaoka, T. and Kadono, T. (2004) Gender difference in daily time and space use among Bangladeshi villagers under arsenic hazard: application of the compact spot-check method. Journal of Biosocial Science. 36(3):317-332.
  • Tanaka, M., Ohtani-Kaneko, R., Yokosuka, M., and Watanabe, C. (2004) Low-dose perinatal diethylstilbestrol exposure affected behaviors and hypothalamic estrogen receptor-α-positive cells in the mouse. Neurotoxicology and Teratology 26: 261-269.
  • Kaori Miyazaki, Kayo Ushijima, Takefumi Kadono, Tsukasa Inaoka, Chiho Watanabe and Ryutaro Ohtsuka (2003) Negative correlation between urinary selsenium and arsenic levels of the residents living in an arsenic-contaminated area in Bangladesh. Journal of Health Science 49(3): 239-242.
  • Chiho Watanabe, Tsukasa Inaoka, Tamano Matsui, Kyoko Ishigaki, Nobuko Murayama and Ryutaro Ohtsuka (2003) Effects of arsenic on younger generations. Journal of Environmental Science and Health A38(1): 129-139.
  • Chiho Watanabe (2002) Modification of Mercury toxicity by selenium: practical importance? Tohoku J. Exp. Med. 196: 71-77.
  • Grazyna Zareba，Rieko Hojo，Karolina M. Zareba，ChihoWatanabe，Vincent P.Markowski，Raymond B. Baggs and Bernard Weiss (2002) Sexually dimorphic alterations of brain cortical dominance in rats prenatally exposed to TCDD. Journal of Applied Toxicology 22: 129-137.
  • Munjoo Bae, Chiho Watanabe, Tsukasa Inaoka, Makiko Sekiyama, Noriko Sudo, Mozammel Haque Bokul and Ryutaro Ohtsuka (2002) Arsenic cooked rice in Bangladesh. The Lancet 360(9348): 1839-1840.
  • Takafumi Kadono, Tsukasa Inaoka, Nobuko Murayama, Kayo Ushijima, Megumi Nagano, Satoshi Nakamura, Chiho Watanabe, Kunihiko Tamaki, and Ryutaro Ohtsuka (2002) Skin manifestations of arsenicosis in two villages in Bangladesh. International Journal of Dermatology 41: 841-846.
  • Watanabe, C: "Environmental arsenic exposure in Bangladesh: Water versus extra-water intake of arsenic." Environmental Sciences 8(5): 459-466. (2001).
  • Ushijima, K., T. Inaoka, T. Kadono, N. Murayama, M. Nagano, S. Nakamura, C. Watanabe, R. Ohtsuka and A. Mozammel Haque Bokul: "Recognition of arsenic contamination by rural Bangladeshi people." Environmental Sciences 8(5): 449-457. (2001).
  • Satoh, H., K. Nakai, C. Kim and C. Watanabe: Neurobehavioral effects of prenatal exposure to methylmercury. Understanding of Minamata disease: Methylmercury poisoning in Minamata and Niigata, Japan. Y. Takizawa and M. Osame. Tokyo, Japan Public Health Association: 94-98. (2001).
  • Watanabe, C., K. Miyazaki, R. Ohtsuka and T. Inaoka: "Arsenic contamination of groundwater: a Bangladesh survey." RIKEN Reviews 35: 19-22. (2001).
  • Watanabe, C., T. Inaoka, T. Kadono, M. Nagano, S. Nakamura, K. Ushijima, N. Murayama, K. Miyazaki and R. Ohtsuka : "Males in rural Bangladeshi communities are more susceptible to chronic arsenic poisoning than females: analyses based on urinary arsenic." Environmental Health Perspectives 109(12): 1265-70. (2001).
  • Watanabe, C., V. Markowski, G. Zareba, C. Cox, S. Stern and B. Weiss: "Motor Activity of rat offsrping after a single prenatal exposure to 2,3,7,8-TCDD." Toxicological Sciences 54 suppl.: 173. (2000).
  • Ejima, A., C. Watanabe, H. Koyama and H Satoh: "Matrix interferences in the analysis of digested biological tissues with inductively coupled plasma-mass spectrometry." Biological Trace Element Research 69(2): 99-109. (1999).
  • Koyama, H., K. Omura, A. Ejima, Y. Kasanuma, C. Watanabe and H. Satoh: "Separation of selenium-containing proteins in human and mouse plasma using tandem high-performance liquid chromatography columns coupled with inductively coupled plasma-mass spectrometry." Analytical Biochemistry 267(1): 84-91.
  • Kurisaki, E., M. Sato, S. Asano, S. Gunji, M. Mochizuki, H. Odajima, H. Wakasa, H. Satoh, C. Watanabe and K. Hiraiwa: "Insufficient metallothionein synthesis in the lung and kidney in human acute inorganic mercury poisoning. " Journal of Health Science 45(6): 309-317. (1999).
  • Watanabe, C., Y. Kasanuma, Y. Dejima and H. Satoh "The effect of prenatal methylmercury exposure on the GSH level and lipid peroxidation in the fetal brain and placenta of mice." Tohoku Journal of Experimental Medicine 187: 121-6. (1999).
  • Watanabe, C., M. Nagano, T. Nakamura, T. Inaoka and R. Ohtsuka: "Arsenic contamination of tubewell water in Bangadesh: distribution of arsenic concentration in small communities." Biomedical Research of Trace Elements 10(3): 187-8. (1999).
  • Watanabe, C., K. Yoshida, Y. Kasanuma, Y. Kun and H. Satoh: "In utero methylmercury exposure differentially affects theactivities of selenoenzymes in the Fetal Mouse Brain." Environmental Research 80(3): 208-214. (1999).
  • Watanabe, C., K. Yin, Y. Kasanuma and H. Satoh: "In utero exposure to methylmercury and Se deficiency converge on the neurobehavioral outcome in mice" Neurotoxicology and Teratology 21(1): 83-8. (1999).
  • Kasanuma, Y., C. Watanabe, C. Y. Kim, K. Yin and H. Satoh: "Effects of mild chronic heat exposure on the concentrations of thiobarbituric acid reactive substances, glutathione, and selenium, and glutathione peroxidase activity in the mouse liver." Tohoku Journal of Experimental Medicine 185(2): 79-87. (1998).
  • Watanabe, C., Y. Kasanuma and H. Satoh: "Deficiency of selenium enhances the K+-induced release of dopamine in the striatum of mice." Neuroscience Letters 236(1): 49-52. (1997).
  • Watanabe, C., C. Y. Kim and H. Satoh: "Tissue-specific modification of selenium concentration by acute and chronic dexamethasone administration in mice." British Journal of Nutrition 78(3): 501-9. (1997).
  • Yin, K., C. Watanabe, H. Inaba and H. Satoh: "Growth and behavioral changes in mice prenatally exposed to methylmercury and heat." Neurotoxicology and Teratology 19(1): 65-71. (1997).
  • Ejima, A., C. Watanabe, H. Koyama, K. Matsuno and H. Satoh: "Determination of selenium in the human brain by graphite furnace atomic absorption spectrometry." Biological Trace Element Research 54(1): 9-21. (1996).
  • Ejima, A., C. Watanabe, H. Koyama and H. Satoh: "Analysis of trace elements in the central nerve tissues with inductively coupled plasma-mass spectrometry." Tohoku Journal of Experimental Medicine 178(1): 1-10. (1996).
  • Koyama, H., Y. Kasanuma, C. Y. Kim, A. Ejima, C. Watanabe, H. Nakatsuka and H. Satoh: "Distribution of selenium in human plasma detected by high performance liquid chromatography-plasma ion source mass spectrometry." Tohoku Journal of Experimental Medicine 178(1): 17-25. (1996).
  • Imai, H., H. Kashiwazaki, T. Suzuki, M. Kabuto, S. Himeno, C. Watanabe, K. Moji, S.-W. Kim, J.-O. Rivera and T. Takemoto: "Selenium levels and glutathione peroxidase activities in blood in an Andean high-altitude population." Journal of Nutritional Science and Vitaminology 41: 349-361. (1995).
  • Kim, C. Y., C. Watanabe, Y. Kasanuma and H. Satoh: "Inhibition of gamma-glutamyltranspeptidase decreases renal deposition of mercury after mercury vapor exposure." Archives of Toxicology 69(10): 722-4. (1995).
  • Kim, C. Y., C. Watanabe and H. Satoh: "Effects of buthionine sulfoximine (BSO) on mercury distribution after Hg(o) exposure." Toxicology 98(1-3): 67-72. (1995).
  • Koyama, H., Y. Kasanuma, C.-Y. Kim, A. Ejima, C. Watanabe, H. Nakatsuka and H. Satoh: "Chromatographic patterns of fasting and postprandial plasma selenium." Journal of Trace Elements in Experimental Medicine 8(2): 88. (1995).
  • Koyama, H., C. Watanabe, H. Satoh, H. Hosokai and S. Tamura: "Consistent relationship between selenium and apolipoprotein A-II concentrations in the sera of fasting middle-aged male abstainers and regular consumers of alcohol." Biological Trace Element Research 50(1): 33-42. (1995).
  • Satoh, H., A. Ejima, C. Watanabe and H. Koyama: "Changes of element concentrations in central nerve tissues after formalin preservation." Journal of Trace Elements in Experimental Medicine 8(2): 115. (1995).
  • Watanabe, C. and H. Satoh: "Effects of prolonged selenium deficiency on open field behavior and Morris water maze performance in mice." Pharmacology Biochemistry and Behavior 51(4): 747-752. (1995).
  • Watanabe, C., H. Imai and H. Kashiwazaki: "Geographical variation in urinary mercury concentrations among populations living in highland and lowland Bolivia." Science of Total Environment 145: 267-73. (1994).
  • Watanabe, C. and H. Satoh: "Brain selenium status and behavioral development in selenium-deficient preweaning mice." Physiology and Behavior 56(5): 927-932. (1994).
  • Yoshida, M., C. Watanabe, H. Satoh, T. Kishimoto and Y. Yamamura: "Milk transfer and tissue uptake of mercury in suckling offspring after exposure of lactating maternal guinea pigs to inorganic or methylmercury." Archives of Toxicology 68: 174-178. (1994).
  • Kashiwazaki, H., H. Imai, J. Orias-Rivera, S.-W. Kim, C. Watanabe, K. Moji, T.-i. Takemoto, K. Takasaka and T. Suzuki: Blood pressure and salt intake in high altitude Bolivian Aymara. Seventh Symposium on Salt. 2: 263-271. (1993).
  • Moriwaka, F., H. Satoh, A. Ejima, C. Watanabe, K. Tashiro, T. Hamada, A. Matsumoto, K. Shima, T. Yanagihara, T. Fukazawa, H. Okumura, Y. Maruo, K. Itoh and K. Yoshida: "Mercury and selenium contents in amyotrophic lateral sclerosis in Hokkaido, the northernmost island of Japan." Journal of Neurological Science 118: 38-42. (1993).
  • Nakatsuka, H., H. Satoh, H. Koyama, C. Watanabe and M. Ikeda "Screening of obese or lean schoolchildren; difficulty in applying "the Japanese weight and height standards for estimating over- and under- weight" to younger people." Nippon Koshu Eisei Zasshi 40(4): 265-72. (1993).
  • Watanabe, C. and H. Satoh "Persistent behavioral effect of prenatal exposure to cigarette smoke in mice." Environmental Sciences 2(1): 1-10. (1993).
  • Watanabe, C., T. Udono, H. Shioiri and H. Satoh:"Change in the level of tissue selenium after a single administration of mercuric chloride in mice." Bulletin of Environmental Contamination and Toxicology 51: 24-29. (1993).
  • Watanabe, C., H. Suzuki and H. Satoh: "Effects of prenatal exposure to cigarette smoke on the growth and neurobehavioral development in offspring of mice." Environmental Sciences 1(3): 143-153. (1992).
  • Watanabe, C., T. Suzuki and N. Matsuo: "Toxicity modification of sodium selenite by a brief exposure to heat or cold in mice." Toxicology 64: 245-253. (1990).
  • Watanabe, C., T. Suzuki, T. Ohba and Y. Dejima "Transient hypothermia and hyperphagia induced by selenium and tellurium compounds in mice." Toxicology Letters 50(2-3): 319-26. (1990).
  • Watanabe, C., B. Weiss, C. Cox and J. Ziriax: "Modification by nickel of instrumental thermoregulatory behavior in rats." Fundamental and Applied Toxicology 14(3): 578-88. (1990).
  • Himeno, S., C. Watanabe, T. Hongo, T. Suzuki, A. Naganuma and N. Imura: "Body size and organ accumalation of mercury and selenium in young harbor seals (phoca vitulina)." Bulletin of Environmental Contamination and Toxicology 42: 503-509. (1989).
  • Iwai　N, C. Watanabe, T. Suzuki, K. T. Suzuki and C. Tohyama: "Metallothionein induction by sodium selenite at two different ambient temperatures in mice." Archives of Toxicology 62(6): 447-51. (1988).
  • Watanabe, C, T. Ohba, H. Nakahara and T. Suzuki: "Modification of lethal, hypothermic and hyperphagic effects of sodium selenite by reduced glutathione in mice." Toxicology 51(2-3): 167-76. (1988).
  • Ohba, T, T. Suzuki, C. Watanabe and S. Himeno: "Transient hyperphagia after sodium selenite injection in mice." Toxicology Letters 39(2-3): 275-81. (1987).
  • Suzuki, T, S. Himeno, T. Hongo, C. Watanabe and H. Satoh: "Mercury-selenium interaction in workers exposed to elemental mercury vapor." Journal of Applied Toxicology 6: 149-153. (1986).
  • Tohyama, C., S. Himeno, C. Watanabe, T. Suzuki and M. Morita: "The relationship of the increased level of metallothionein with heavy metal levels in the tissue of harbor seal (Phoca vitulina)." Ecotoxicology and Environmental Safety 12: 85-94. (1986).
  • Watanabe, C. and T. Suzuki: "Sodium selenite-induced hypothermia in mice: indirect evidence for a neural effect." Toxicology and Applied Pharmacology. 86: 372-379. (1986).
  • Himeno, S., C. Watanabe and T. Suzuki: "Urinary biochemical changes in workers exposed to mercury vapor." Industrial Health 24: 151-155. (1985)
  • Hongo, T., C. Watanabe, S. Himeno and T. Suzuki: "Relationship between erythrocyte mercury and selenium in erythrocyte, plasma, and urine." Nutrition Research 5: 1285-1289. (1985)
  • Watanabe, C. and T. Suzuki: "Effect of fasting on hypoxia tolerance of mice in relation to oxygen consumption and heart rate." Aviation, Space, and Environmental Medicine. 56: 1198-1202. (1985)

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  • ■　原著論文（和文）
  • 藤巻可弓，荒川千夏子，吉永淳，渡辺知保，芹澤滋子，今井秀樹，白石寛明，水元賀文：尿中代謝産物排泄量から推定した 日本人妊婦のビスフェノールＡ推定量　日本衛生学雑誌59 403-408 (2004)
  • 大塚柳太郎，渡辺知保，宮崎賀織，門野岳史，牛島佳代，稲岡司，中村哲，村山伸子：バングラディシュの砒素汚染－ ナワブカンジ地域における医学生態学調査“日本職業・災害医学会誌49（3別冊）198-202．(2001)

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  • ■　総説（英文）
  • Watanabe, C., T. Inaoka, T. Matsui, K. Ishigaki, N. Murayama and R. Ohtsuka: "Effects of arsenic on younger generations." Journal of Environmental Science and Health - Part A A38: 129-139. (2003).
  • Watanabe, C: "Modification of mercury toxicity by selenium: Practical importance?" Tohoku Journal of Experimental Medicine 196: 71-77. (2002).
  • Watanabe, C., Ed. Special issue on the arsenic problems in developing countries. Environmental Sciences. (2001).
  • Rice, D. C., A. M. E. de Duffard, R. Duffard, A. Iregren, H. Satoh and C. Watanabe: "Lessons for neurotoxicology from selected model compounds." Environmental Health Perspectives 104 Suppl. 2: 205-215. (1996).
  • Watanabe, C. and H. Satoh: "Evolution of our understanding of methylmercury as a health threat." Environmental Health Perspectives 104 Suppl. 2: 367-379. (1996).

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  • ■　総説（和文）
  • 渡辺知保： "セレンによる水銀毒性の修飾." 医学のあゆみ202(11): 899-902. (2002)
  • 渡辺知保：セレン欠乏と脳機能：メチル水銀毒性におけるその意義　日本衛生学雑誌55：581-589（2001）
  • 渡辺知保： "脳におけるセレン：特異的機能はあるのか？." Biomedical Research on Trace Elements” 12(3): 197-206. (2001)
  • 渡辺知保: セレン欠乏と神経行動機能." Biomedical Research on Trace Elements11(4):331-2. (2000).

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  • ■　単行本分担執筆（英文・和文）
  • Watanabe, C: Roles of selenium in funcion of the brain. in H. Lieberman, R. Kanarek and C. Prasad (eds) “Nutritional neuroscience: overview of an emerging field”. Boca Raton, USA, CRC Press: 307-330 (2005)
  • 渡辺知保，大谷－金子律子，田中美加：周生期におけるジエチルスチルベストロール曝露の行動影響　井口泰泉， 井上達編「生態統御システムと内分泌攪乱」シュプリンガー・フェアラーク，東京:181-188（2005）
  • 渡辺知保：水の機能. 太田猛彦，住明正，池淵周一，田渕俊雄，眞柄泰基，松尾友矩，大塚柳太郎編, 「水の事典」朝倉書店: 488-501. (2004)
  • 渡辺知保：水圧による疾病. 太田猛彦，住明正，池淵周一，田渕俊雄，眞柄泰基，松尾友矩，大塚柳太郎編, 「水の事典」 朝倉書店: 532-537. (2004).
  • 渡辺知保，大塚柳太郎：生態毒性学（エコトキシコロジー）.「中毒学-基礎・臨床・社会医学」. 荒木俊一, 朝倉書店: 341-344（2002).
  • 大塚柳太郎， 河辺俊雄， 高坂宏一，渡辺知保， 阿部卓：「人類生態学」 東大出版会. (2002).
  • 藤田博美，渡辺知保：ヘムおよびストレス蛋白質の遺伝子制御．井上正康編「活性酸素とシグナル伝達」， 講談社サイエンティフィク，57-67，（1996）
  • 渡辺知保：必須元素としてのセレン. Toxicology Today -中毒学から生体防御の科学へ-. 佐藤洋編. 京都, 金芳堂: 157-164. (1994).

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